Comedy directed by Henry Selick based on Kaja Blackley's graphic novel and starring Brendan Fraser and Bridget Fonda. Happy to have just sold his character Monkeybone to a television company, cartoon artist Stu Miley (Fraser) is getting ready to propose to his girlfriend Julie (Fonda) when he is involved in a terrible accident. Sinking deep into a coma, Stu is then joined by Monkeybone (voice of John Turturro) in an unlikely journey in a bizarre nightmare realm.

But Monkeybone escapes from the dream and begins creating all kinds of libidinous havoc in the real world. Can Stu somehow find a way back and put a stop to this animated simian chaos?

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