There were nine who escaped. Three are dead. He is Number Four.

D.J. Caruso (Eagle Eye, Disturbia) helms an action-packed thriller about an extraordinary young man, John Smith (Alex Pettyfer), who is a fugitive on the run from ruthless enemies sent to destroy him. Changing his identity, moving from town to town with his guardian Henri (Timothy Olyphant – Die Hard 4.0), he is always the new kid with no ties to his past. In the small Ohio town he now calls home, John encounters unexpected, life-changing events—his first love (Dianna Agron), powerful new abilities and a connection to the others who share his incredible destiny.